I sent two 5x7s, a LOR and SASE to Seth MacFarlane on Sept. 27th 2018. I got both my pictures back autographed (with one personalized) on Nov. 22nd 2018! I used the address in the database:
Seth MacFarlane
Family Guy Studios
Fox Television
10201 West Pico Blvd.
Los Angeles, CA 90064
USA